Xinzhong Wu
Qinzhou University, China
Title: Developmental and evolutionary immunity of marine molluscan animals: Immune diversity and evolution
Biography
Biography: Xinzhong Wu
Abstract
Recently relevant findings from molluscs expanded our traditional concepts in the field of innate immunity, namely from simple and homogeneous invertebrate immune system to the sophisticated and diversified innate immune system to host defense against pathogens, which include the effect of molecular diversity or increased abundance on immune diversity of molluscs, pathways that involved in molluscan immunity and how mollusk and pathogen interact at the molecular level. In particular the completion of related complete genome sequence from mollusc species gives the opportunity to examine the evolution of gene families, sequence divergence from different components of the innate immune system and the origins of some novel immune-related genes and their families in evolution. Here, we detailed some of the examples among these mollusc models to emphasize the diversities of the immune genes, their families and the diversified responses of innate immunity. We sought to discuss the drives or evolutionary dynamics of differences currently within the innate immune system from the present study existing in fact. In addition, we put forward the necessity of studying on comparative immune diversity with different invertebrate models.